887747-74-2

Upstream product

• 339091-26-8 1,2,3,5-tetra-O-acetyl-D-xylofuranose 
• 887747-64-0 p-tolyl 2,3-di-O-benzyl-5-O-trityl-1-thio-β-L-xylofuranoside 
• 887747-63-9 p-tolyl 5-O-trityl-1-thio-β-L-xylofuranoside 
• 887747-65-1 p-tolyl 2,3-di-O-benzyl-1-thio-β-L-xylofuranoside 
• 887747-61-7 p-tolyl 2,3,5-tri-O-acetyl-1-thio-β-L-xylofuranoside 
• 887747-62-8 p-tolyl 1-thio-β-L-xylofuranoside 
• 887747-57-1 p-tolyl 2,3-di-O-benzyl-5-O-toluenesulfonyl-1-thio-β-L-xylofuranoside 
• 73045-58-6 methyl 2,4,6-tri-O-benzyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

IMMUNOMODULATORY SACCHARIDE COMPOUNDS

Compounds comprising a saccharide molecule and a 5-deoxy-5-methylthio-xylofuranose (MTX) moiety or a 5-deoxy-5-methylsulfoxy-xylofuranose (MSX) moiety, and use of such compounds in methods for modulating inflammation and immune responses.

The 5-deoxy-5-methylthio-xylofuranose residue in mycobacterial lipoarabinomannan. Absolute stereochemistry, linkage position, conformation, and immunomodulatory activity

Mycobacteria produce a cell-surface glycoconjugate, lipoarabinomannan (LAM), which has been shown to be a potent modulator of the immune response that arises from infection by these organisms. Recently, LAM from the human pathogens Mycobacterium tuberculo