887909-19-5Relevant academic research and scientific papers
Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis
Poulsen, Sally-Ann,Bornaghi, Laurent F.
, p. 3275 - 3284 (2006)
A fragment-based drug discovery approach to the synthesis and identification of small molecule inhibitors of bovine carbonic anhydrase II (bCA II) is described. The classical bCA II recognition fragment is an aromatic sulfonamide (ArSO2NH2
