88791-91-7

Upstream product

• 539-48-0 p-xylylidenediamine 
• 74-88-4 methyl iodide 
• 19851-38-8 1,4-bis-(N,N-dimethylaminomethyl)benzene 

Downstream Products

• 88791-92-8 C₁₄H₂₆N₂⁽²⁺⁾*4CHI₃*2I^(1-) 

Relevant academic research and scientific papers

Curare-like camphor derivatives and their biological activity

The synthesis of symmetric dimeric camphor derivatives containing two quaternary nitrogen atoms was performed and their myorelaxant activity in mice was evaluated. For the comparison, some salts derived from meta-and para-xylylene dibromides were synthesi

The incremental approach to noncovalent interactions: Coulomb and van der waals effects in organic ion pairs

The equilibria of 10 ion pairs with aromatic units in one or both ions are determined in water by UV/vis and partially by NMR and conductivity experiments, showing in most cases satisfactory agreement. UV/vis measurements at different wavelengths usually exhibit weaker 1:2, in addition to 1:1, complexes. On the basis of a generalized principle of additive binding increments, the results from about 40 ion pairs - many from the literature - show a surprisingly constant Coulomb increment of ΔG = 5 ± 1 kJ/mol per single salt bridge. The van der Waals forces in the aromatic ion pairs also lead to a linear increase of the complexation strength with the number of aryl groups in the complexes. A corresponding two-term correlation yields, in agreement with other studies, a vdW increment of 1-2 kJ/mol per aryl unit, which is shown to be due to ion-induced dipoles in the π-system. Conformations were partially modeled with force field calculations (CHARMm); they are in qualitative agreement with complexation-induced shifts obtained from NMR titrations. The CIS-NMR values explain deviations from the correlations for three ion pairs due to steric hindrance and contradict edge-to-face arrangements of benzene rings. Charge-transfer (CT) interactions, although visible in typical UV/vis absorptions, do not contribute significantly (0.5 kJ/mol) to the associations. Selected measurements with less polar solvents added show the expected binding increase but no correlation with the bulk dielectric constant.

Inclusion Compounds of Organic Onium Salts, IV. Organyl Ammonium Hosts as Versatile Clathrate Formers

The organyl-oligo-ammonium compounds 1 - 25 and their clathrates with a variety of low molecular weight neutral compounds, especially solvent molecules, are prepared.The inclusion capacity of the new clathrands can be explained by interstices in the host lattice.The conformational flexibility of the voluminous onium branches is responsible for the great number of clathrates; their stability depends on the ion lattice.The X-ray analysis of the ethanol clathrate of the onium host 8 shows that one ethanol molecule is surrounded by the host molecules in a cage-type manner.The great variety of the inclusions obtained up to now demonstrates that the oligo onium host compounds have to be considered as the most universal clathrands of organic chemistry.Hints are given for the syntheses of new onium clathrates.