887933-96-2Relevant academic research and scientific papers
Solubilized phenyl-pyrazole ureas as potent, selective 5-HT2A inverse-agonists and their application as antiplatelet agents
Dosa, Peter I.,Strah-Pleynet, Sonja,Jayakumar, Honnappa,Casper, Martin,Decaire, Marc,Xiong, Yifeng,Lehmann, Juerg,Choi, Karoline,Elwell, Katie,Wong, Amy,Webb, Robert R.,Adams, John W.,Ramirez, Juan,Richman, Jeremy G.,Thomsen, William,Semple, Graeme,Teegarden, Bradley R.
scheme or table, p. 5486 - 5489 (2010/04/26)
Potent 5-HT2A inverse-agonists containing phenyl-pyrazole ureas with an amino side chain were identified. Optimization of this series resulted in selective compounds that proved effective in modulating 5HT-induced amplification of ADP-stimulate
