88796-12-7Relevant academic research and scientific papers
SUBSTITUTED 3- AND 4- AMINOMETHYLPIPERIDINES FOR USE AS BETA-SECRETASE IN THE TREATMENT OF ALZHEIMER’S DISEASE
-
Page/Page column 21-22; 42; 43, (2008/06/13)
The invention relates to novel compounds, which are substituted chiral or achiral derivatives of 3- or 4- aminomethylpiperidine of the general formula (I). The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of general formula (I) and especially their use as inhibitors of beta-secretases for the treatment of Alzheimer’s disease.
3-amino-2-aryl quinuclidines
-
, (2008/06/13)
Compounds of the formula STR1 wherein R1 is hydrogen or (C1 -C6)alkyl; R2 is phenyl, pyridyl, thienyl or furyl, and R2 may optionally be substituted with from one to three substituents independently s
Anti-virally active pyridazinamines
-
, (2008/06/13)
Anti-virally active pyridazinamines, compositions containing the same and methods of treating viral diseases in warm-blooded animals.
