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methyl 3-(3-bromophenyl)-2-(tert-butoxycarbonylamino)-2-methylpropanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

887969-56-4

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  • methyl 3-(3-bromophenyl)-2-(tert-butoxycarbonylamino)-2-methylpropanoate

    Cas No: 887969-56-4

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887969-56-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 887969-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,9,6 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 887969-56:
(8*8)+(7*8)+(6*7)+(5*9)+(4*6)+(3*9)+(2*5)+(1*6)=274
274 % 10 = 4
So 887969-56-4 is a valid CAS Registry Number.

887969-56-4Relevant articles and documents

Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors

Lindsley, Stacey R.,Moore, Keith P.,Rajapakse, Hemaka A.,Selnick, Harold G.,Young, Mary Beth,Zhu, Hong,Munshi, Sanjeev,Kuo, Lawrence,McGaughey, Georgia B.,Colussi, Dennis,Crouthamel, Ming-Chih,Lai, Ming-Tain,Pietrak, Beth,Price, Eric A.,Sankaranarayanan, Sethu,Simon, Adam J.,Seabrook, Guy R.,Hazuda, Daria J.,Pudvah, Nicole T.,Hochman, Jerome H.,Graham, Samuel L.,Vacca, Joseph P.,Nantermet, Philippe G.

, p. 4057 - 4061 (2008/02/10)

This Letter describes the design and synthesis of tertiary carbinamine macrocyclic inhibitors of the β-secretase (BACE-1) enzyme. These macrocyclic inhibitors, some of which incorporate novel P2 substituents, display a 2- to 100-fold increase in potency r

MACROCYCLIC TERTIARY AMINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

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Page/Page column 55, (2010/11/08)

The present invention is directed to macrocyclic tertiary amine compounds represented by general formula (I), which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

MACROCYCLIC AMINOPYRIDYL BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

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Page/Page column 43, (2010/11/08)

The present invention is directed to macrocyclic aminopyridyl compounds represented by general formula (I), which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved,

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