887969-81-5

Basic information

• Product Name: 3-(methoxycarbonyl)-5-[(methylsulfonyl)oxy]benzoic acid
• Synonyms: 3-(methoxycarbonyl)-5-[(methylsulfonyl)oxy]benzoic acid
• CAS NO: 887969-81-5
• Molecular Weight: 274.251
• Mol File: 887969-81-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(methoxycarbonyl)-5-[(methylsulfonyl)oxy]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(methoxycarbonyl)-5-[(methylsulfonyl)oxy]benzoic acid(887969-81-5)
• EPA Substance Registry System: 3-(methoxycarbonyl)-5-[(methylsulfonyl)oxy]benzoic acid(887969-81-5)

Safety Data

• Hazardous Substances Data: 887969-81-5(Hazardous Substances Data)

Upstream product

• 13036-02-7 Dimethyl 5-hydroxyisophthalate 
• 887969-80-4 dimethyl 5-(methylsulfonyloxy)isophthalate 

Downstream Products

• 1067648-74-1 5-methanesulphonyloxy-N-((R)-1-phenyl-ethyl)-isophthalamic acid methyl ester 
• 1067648-25-2 methanesulphonic acid 3-[(1S,2S,4S)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-benzyloxymethyl-2-hydroxy-5-methyl-hexylcarbamoyl]-5-((R)-1-phenyl-ethylcarbamoyl)-phenyl ester 
• 1067648-76-3 (R)-3-(methylsulfonyloxy)-5-(1-phenylethylcarbamoyl)benzoic acid 
• 887969-82-6 tert-butyl methyl 5-[(methylsulfonyl)oxy]isophthalate 

Relevant articles and documents

AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES

The invention provides compounds of the formula (I). N-oxides, addition salts, quaternary amines, metal complexes, stereochemically isomeric forms and metabolites thereof, wherein W is H, C1-C6alkyl, C3-C6cycloalkyl, aryl or heterocyclyl; Q is aryl or heterocyclyl; A is a five or six membered saturated, partially unsaturated or aromatic ring; D is formula (II) or formula (III); and the other variables are as defined in the specification. The compounds of the invention are inhibitors of aspartyl proteases such as renin and BACE and are among other things useful for the treatment and/or prophylaxis of conditions associated with activities of the RAS, such as hypertension, heart failure and renal insufficiency and for the treatment and or prophylaxis of conditions associated with BACE activity such as of Alzheimer's disease.