888015-87-0Relevant academic research and scientific papers
Synthesis of [14C]-radiolabelled entecavir
Ogan, Marc D.,Kucera, David J.,Pendri, Yadagiri R.,Rinehart, J. Kent
, p. 645 - 655 (2005)
Radiolabelled [l4C]entecavir, (1), was prepared in 12 steps from (1S,2R,3S,5R)-3-(benzyloxy)-2-(benzyloxymethyl)-6-oxa-bicyclo[3.1.0]hexane 2. The chemical yield of [l4C]entecavir was 14% from the epoxide 2. Introduction of [14
