88802-63-5Relevant academic research and scientific papers
Total Synthesis of (+/-)-Aphidicolin and (+/-)-β-Chamigrene
Ireland, Robert E.,Dow, William C.,Godfrey, Jollie D.,Thaisrivongs, Suvit
, p. 1001 - 1013 (2007/10/02)
Total synthesis of (+/-)-chamigrene and (+/-)-aphidicolin are described.Both approaches are based on the spiroannelation of related α-methylene ketones through first hetero-Diels-Alder condensation and then Claisen rearrangement of the derived allyl vinyl
