888039-39-2

Basic information

• Product Name: 2-Propenoic acid, 3-chloro-3-cyclohexyl-2-iodo-, ethyl ester, (2E)-
• CAS NO: 888039-39-2
• Molecular Formula: C11H16ClIO2
• Molecular Weight: 342.604
• Mol File: 888039-39-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-chloro-3-cyclohexyl-2-iodo-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-chloro-3-cyclohexyl-2-iodo-, ethyl ester, (2E)-(888039-39-2)
• EPA Substance Registry System: 2-Propenoic acid, 3-chloro-3-cyclohexyl-2-iodo-, ethyl ester, (2E)-(888039-39-2)

Safety Data

• Hazardous Substances Data: 888039-39-2(Hazardous Substances Data)

Upstream product

• 33547-94-3 cyclohexyl-propynoic acid ethyl ester 

Downstream Products

• 1038863-21-6 ethyl (Z)-3-chloro-3-cyclohexyl-2-(4-methoxyphenyl)but-2-enoate 
• 1258222-35-3 (6Z)-6-cyclohexyl-8-ethoxy-8-oxooct-6-enyl benzoate 
• 87666-40-8 ethyl (2E)-3-cyclohexyl-3-phenyl prop-2-enoate 
• 888039-50-7 (Z)-ethyl 2-(chloro(cyclohexyl)methylene)-4-phenylbut-3-ynoate 
• 928056-48-8 (Z)-ethyl 3-chloro-3-cyclohexyl-2-iodoacrylate 

Relevant articles and documents

Single-isomer iodochlorination of alkynes and chlorination of alkenes using tetrabutylammonium iodide and dichloroethane

(Chemical Equation Presented) The efficient formation of single-isomer, differentially halogenated alkenes and alkanes is described. These structures were generated by treatment of the appropriate alkyne or alkene with tetrabutylammonium iodide in refluxing dichloroethane. This process is highly selective as evidenced by control experiments using ICl. Treatment of the same alkenes and alkynes directly with iodine monochloride resulted in complex, inseparable mixtures of regio- and stereoisomers. Mechanistic studies indicated that the Bu4NI reaction most likely proceeded through the slow generation of ICl. Complexation of ICl with Bu4NI is also a key controlling element that leads to perfect regio-, chemo-, and stereoselectivity in these processes.