888488-17-3

Basic information

• Product Name: (3R,4R,5R,6R,8R,9S,10R,11R,12S,13S)-3,11-bis-[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-9-hydroxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxybenzyloxy]pentadec-7-one
• Synonyms: (3R,4R,5R,6R,8R,9S,10R,11R,12S,13S)-3,11-bis-[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-9-hydroxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxybenzyloxy]pentadec-7-one
• CAS NO: 888488-17-3
• Molecular Weight: 853.5
• Mol File: 888488-17-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R,5R,6R,8R,9S,10R,11R,12S,13S)-3,11-bis-[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-9-hydroxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxybenzyloxy]pentadec-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5R,6R,8R,9S,10R,11R,12S,13S)-3,11-bis-[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-9-hydroxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxybenzyloxy]pentadec-7-one(888488-17-3)
• EPA Substance Registry System: (3R,4R,5R,6R,8R,9S,10R,11R,12S,13S)-3,11-bis-[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-9-hydroxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxybenzyloxy]pentadec-7-one(888488-17-3)

Safety Data

• Hazardous Substances Data: 888488-17-3(Hazardous Substances Data)

Upstream product

• 207680-83-9 (2S,4R,5R,6R)-2-benzoyloxy-7-benzyloxy-5-tert-butyldimethylsilyloxy-4,6-dimethylheptan-3-one 
• 207680-79-3 (2S,4R,5R,6R)-7-(benzyloxy)-5-hydroxy-4,6-dimethyl-3-oxoheptan-2-yl benzoate 
• 167842-02-6 (2S,4R,5R)-2-benzoyloxy-5-(tert-butyldimethylsilyloxy)-4,6-dimethylheptan-3-one 
• 161985-39-3 (2S,4R,5R)-2-benzoyloxy-5-hydroxy-4,6-dimethylheptan-3-one 
• 160666-92-2 (S)-2-benzoyloxypentan-3-one 
• 116660-67-4 (2S,3R)-3-<(tert-Butyldimethylsilyl)oxy>-2,4-dimethylpentanal 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 888488-39-9 (2S,4R,5R,6R,7R)-2-benzoyloxy-7-tert-butyldimethylsilyloxy-5-triethylsilyloxy-4,6,8-trimethylnon-3-one 
• 888488-15-1 (3S,4S,5R,6R)-7-benzyloxy-5-tert-butyldimethylsilyloxy-3-(p-methoxybenzyloxy)-4,6-dimethylheptane 
• 888488-42-4 (2S,4R,5R,6S,7R)-2-benzoyloxy-7-tert-butyldimethylsilyloxy-5-hydroxy-4,6,8-trimethylnon-3-one 
• 888488-34-4 (2R,3R,4S,5S)-3-(tert-butyldimethylsilyloxy)-5-(p-methoxybenzyloxy)-2,4-dimethylheptan-1-ol 
• 888488-14-0 (3S,4S,5R,6R)-7-benzyloxy-5-tert-butyldimethylsilyloxy-4,6-dimethylheptan-3-ol 
• 888488-12-8 (4R,5R,6R)-7-benzyloxy-5-tert-butyldimethylsilyloxy-4,6-dimethylheptan-3-one 
• 888488-09-3 (2S,3S,4S,5S)-3-(tert-butyldimethylsilyloxy)-5-(p-methoxybenzyloxy)-2,4-dimethylheptanal 

Downstream Products

• 888488-07-1 (3R,4R,5R,6R,8R,10S,11S,12S,13S)-3,11-bis[tert-butyldimethylsilyloxy]-5-triethylsilyloxy-2,4,6,8,10,12-hexamethyl-13-[4-methoxy-benzyloxy]pentadeca-7,9-dione 

Relevant articles and documents

A retro-Claisen approach to dolabriferol

The protected precursor 30 to dolabriferol was generated by a DBU-induced, ester-forming, retro-Claisen process. The required linear carbon chain present in 22 was synthesized by a stereoselective lithium aldol reaction. The necessary aldehyde and ketone