88852-57-7 Usage
General Description
The chemical "(1R,2S,3R,5R)-3-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol" is a complex compound with a cyclopentane ring and a purinyl group. It consists of a cyclopentane-1,2-diol structure with a hydroxymethyl group and an amino group, as well as a 6-chloro-9H-purin-9-yl group attached to the cyclopentane ring. (1R,2S,3R,5R)-3-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol is likely to have biological activity due to the presence of the purinyl group, which is often found in biologically active molecules such as nucleic acids and ATP. (1R,2S,3R,5R)-3-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)cyclopentane-1,2-diol may have potential uses in medicine, biochemistry, or pharmaceutical research due to its unique structure and potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 88852-57-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,8,5 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88852-57:
(7*8)+(6*8)+(5*8)+(4*5)+(3*2)+(2*5)+(1*7)=187
187 % 10 = 7
So 88852-57-7 is a valid CAS Registry Number.
88852-57-7Relevant articles and documents
Synthesis and antiviral evaluation of carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines
Shealy,Clayton,Arnett,Shannon
, p. 670 - 674 (2007/10/02)
Carbocyclic analogues of ribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines were prepared from the 2-amino-6-chloropurine ribofuranoside analogue and the 2-amino-6-chloro-8-azapurine ribofuranoside analogue, respectively. Analogues of purine ribofuranosides with the chloro, amino, methylamino, or methylthio group at position 6, the thioguanosine analogue, and the previously reported guanosine analogue were evaluated in vitro against herpes simplex virus, type 1 (HSV-1). 8-Azapurine ribofuranoside analogues with the chloro, amino, or methylthio group at position 6 and the previously reported 8-azaguanosine analogue were also evaluated against HSV-1. The carbocyclic analogue of 2,6-diaminopurine ribofuranoside is highly active against HSV-1 and, also, against vaccinia virus. The 2-amino-6-chloropurine, 2-amino-6-(methylamino)purine, and the 2,6-diamino-8-azapurine derivatives also demonstrated significant activity against HSV-1.
