888716-23-2Relevant academic research and scientific papers
Synthesis of a new series of 2,7-diazaspirononan-1-ones and study of their cholinergic properties
Cignarella, G.,Villa, S.,Barlocco, D.
, p. 115 - 120 (1994)
A new series of substituted 2,7-diazaspirononan-1-ones (1a-l), structurally related to the muscarinic agonist RS-86, has been synthesized and tested for cholinergic properties both in vitro and in vivo.None of the compounds showed significant cholinergic properties at either the central or peripheral level.A possible explanation for the lack of activity is given.Alzheimer's disease / cholinergic system / RS-86 / muscarinic agonists
Use of certain imidazol carbazols in treating stress-related manic-depressive disorders
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, (2008/06/13)
Use of a mono or bicyclic carbocyclic, or heterocyclic carboxylic, acid ester or amide or an imidazolyl carbazol in the manufaccure of a medicament suitable for the treatment of stress-related psychiatric disorders, for increasing vigilance, for the treatment of rhinitis or serotonin-induced disorders and/or coadministration with another active agent to increase the bioavailability thereof, or for nasal administration.
