888716-49-2

Basic information

• Product Name: (+)-(2R,3S)-isopropyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate
• Synonyms: (+)-(2R,3S)-isopropyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate
• CAS NO: 888716-49-2
• Molecular Weight: 357.406
• Mol File: 888716-49-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-(2R,3S)-isopropyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(2R,3S)-isopropyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate(888716-49-2)
• EPA Substance Registry System: (+)-(2R,3S)-isopropyl 3-(benzyloxycarbonylamino)-2-hydroxy-3-phenylpropanoate(888716-49-2)

Safety Data

• Hazardous Substances Data: 888716-49-2(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 60512-85-8 (E)-isopropyl cinnamate 
• 1262306-22-8 benzyloxycarbonylamino-4-chlorobenzoate 
• 3426-71-9 Benzyl N-hydroxycarbamate 

Downstream Products

• 190181-76-1 C₁₀H₉NO₄ 
• 351526-56-2 (-)-(4S,5R)-methyl 2-oxo-4-phenyloxazolidine-5-carboxylate 
• 5817-02-7 (1S,2S)-2-amino-1-phenyl-1,3-propanediol 

Relevant articles and documents

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction

Ethyl-(7), benzyl-(8), tert-butyl-(9), and fluorenylmethyl-4- chlorobenzoyloxycarbamates (10) have been prepared as storable and easy-to-prepare nitrogen sources for use in the intermolecular Sharpless aminohydroxylation reaction and its asymmetric variant. These reagents were found to be effective under base-free reaction conditions. The scope and limitations of these methods have been explored using a variety of alkenes, among which, trans-cinnamates, in particular, proved to be good substrates.