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888721-07-1

6-Phenylpyridine-2-carboxylic acid N-oxide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 888721-07-1 Structure

  • Basic information

    1. Product Name: 6-Phenylpyridine-2-carboxylic acid N-oxide
    2. Synonyms: 6-Phenylpyridine-2-carboxylic acid N-oxide
    3. CAS NO:888721-07-1
    4. Molecular Formula: C12H9NO3
    5. Molecular Weight: 215.20476
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 888721-07-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-Phenylpyridine-2-carboxylic acid N-oxide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-Phenylpyridine-2-carboxylic acid N-oxide(888721-07-1)
    11. EPA Substance Registry System: 6-Phenylpyridine-2-carboxylic acid N-oxide(888721-07-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 888721-07-1(Hazardous Substances Data)

888721-07-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 888721-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,8,7,2 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 888721-07:
(8*8)+(7*8)+(6*8)+(5*7)+(4*2)+(3*1)+(2*0)+(1*7)=221
221 % 10 = 1
So 888721-07-1 is a valid CAS Registry Number.

888721-07-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-oxido-6-phenylpyridin-1-ium-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-carboxy-6-phenylpyridine 1-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:888721-07-1 SDS

888721-07-1Relevant articles and documents

FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF

-

Page/Page column 154, (2010/01/29)

The present invention provides a fused heterocyclic derivative having a strong kinase inhibitory activity and use thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specificatio

Discovery of pyrrolopyridine-pyridone based inhibitors of met kinase: Synthesis, X-ray crystallographic analysis, and biological activities

Kyoung, Soon Kim,Zhang, Liping,Schmidt, Robert,Cai, Zhen-Wei,Wei, Donna,Williams, David K.,Lombardo, Louis J.,Trainor, George L.,Xie, Dianlin,Zhang, Yaquan,An, Yongmi,Sack, John S.,Tokarski, John S.,Darienzo, Celia,Kamath, Amrita,Marathe, Punit,Zhang, Yueping,Lippy, Jonathan,Jeyaseelan Sr., Robert,Wautlet, Barri,Henley, Benjamin,Gullo-Brown, Johnni,Manne, Veeraswamy,Hunt, John T.,Fargnoli, Joseph,Borzilleri, Robert M.

experimental part, p. 5330 - 5341 (2009/07/01)

Conformationally constrained 2-pyridone analogue 2 is a potent Met kinase inhibitor with an IC50 value of 1.8 nM. Further SAR of the 2-pyridone based inhibitors of Met kinase led to potent 4-pyridone and pyridine N-oxide inhibitors such as 3 and 4. The X-ray crystallographic data of the inhibitor 2 bound to the ATP binding site of Met kinase protein provided insight into the binding modes of these inhibitors, and the SAR of this series of analogues was rationalized. Many of these analogues showed potent antiproliferative activities against the Met dependent GTL-16 gastric carcinoma cell line. Compound 2 also inhibited Flt-3 and VEGFR-2 kinases with IC50 values of 4 and 27 nM, respectively. It possesses a favorable pharmacokinetic profile in mice and demonstrates significant in vivo antitumor activity in the GTL-16 human gastric carcinoma xenograft model.

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