88874-23-1

Usage

InChI:InChI=1/C7H8N2O2/c1-5-8-4-6(9-5)2-3-7(10)11/h2-4H,1H3,(H,8,9)(H,10,11)/p-1/b3-2+

Upstream product

• 141-82-2 malonic acid 
• 35034-22-1 2-methylimidazole-4⁽⁵⁾-carbaldehyde 

Downstream Products

• 1427192-09-3 1-(3,5-cis-dimethylpiperidin-1-yl)-3-(4,6-dimethoxy-2-hydroxyphenyl)-3-(4-methylimidazol-4-yl)propan-1-one 

Relevant academic research and scientific papers

Amido compounds as RORγt modulators and uses thereof

Amido compounds are disclosed that have a formula represented by the following: and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graft-versus-host disease.

AMIDO COMPOUNDS AS RORGAMMATMODULATORS AND USES THEREOF

Amido compounds are disclosed that have a formula represented by the following: 1 and wherein Cy1, Cy2, n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune disorders, cancer, and graftversus-host disease