888959-48-6

Basic information

• Product Name: 1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glycerol
• Synonyms: 1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glycerol
• CAS NO: 888959-48-6
• Molecular Weight: 419.634
• Mol File: 888959-48-6.mol

Chemical Properties

• CAS DataBase Reference: 1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glycerol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glycerol(888959-48-6)
• EPA Substance Registry System: 1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glycerol(888959-48-6)

Safety Data

• Hazardous Substances Data: 888959-48-6(Hazardous Substances Data)

Upstream product

• 6404-29-1 6-(tert-butoxycarbonylamino)hexanoic acid 

Downstream Products

• 888959-55-5 6-tert-butoxycarbonylamino-hexanoic acid 2-(tert-butyl-dimethyl-silanyloxy)-3-{[2-(3-{2-[2-(2-{2-[4-(4-dimethylamino-phenylazo)-benzoylamino]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionylamino)-ethoxy]-hydroxy-phosphoryloxy}-propyl ester 
• 888959-52-2 6-tert-butoxycarbonylamino-hexanoic acid 3-O-({2-[3-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propyonylamino]-ethoxy}-benzyloxy-phosphoryloxy)-2-O-(tert-butyl-dimethylsilyl)-sn-glyceryl ester 
• 888959-50-0 benzyloxy (3-[1-O-[6-(N-Boc-amino)hexanoyl]-2-O-tert-butyldimethylsilyl-sn-glyceryl])(N,N-diisopropylamino)phosphine 

Relevant articles and documents

Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity

Lysophospholipase D (lysoPLD), also known as autotaxin (ATX), is an important source of the potent mitogen lysophosphatidic acid (LPA). Two fluorogenic substrate analogues for lysoPLD were synthesized in nine steps from (S)-PMB-glycerol. The substrates (FS-2 and FS-3) show significant increases in fluorescence when treated with recombinant ATX and have potential applications in screening for this emerging drug target.