888969-39-9Relevant academic research and scientific papers
Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2
Choi, Ha-Soon,Wang, Zhicheng,Richmond, Wendy,He, Xiaohui,Yang, Kunyong,Jiang, Tao,Karanewsky, Donald,Gu, Xiang-ju,Zhou, Vicki,Liu, Yi,Che, Jianwei,Lee, Christian C.,Caldwell, Jeremy,Kanazawa, Takanori,Umemura, Ichiro,Matsuura, Naoko,Ohmori, Osamu,Honda, Toshiyuki,Gray, Nathanael,He, Yun
, p. 2689 - 2692 (2007/10/03)
A series of 2-amino-9-aryl-7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized as focal adhesion kinase (FAK) inhibitors using molecular modeling in conjunction with a co-crystal structure. Chemistry was developed to introduce functionality onto th
