88907-83-9Relevant articles and documents
THE SYNTHESIS OF (+/-)-ISOPTYCHANOLIDE BY APPLICATION OF THE α-ALKYNONE CYCLISATION
Solaja, Bogdan,Huguet, Joan,Karpf, Martin,Dreiding, Andre S.
, p. 4875 - 4886 (2007/10/02)
The first synthesis of racemic isoptychanolide (2), a stereoisomer of natural ptychanolide (1), which differs in the configuration of the oxirane function, is reported.The key steps were an α-alkinone cyclisation (5 4, gas phase flow thermolysis at 62