88908-87-6

Basic information

• Product Name: Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-methylene-, methyl ester (9CI)
• Synonyms: Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-methylene-, methyl ester (9CI)
• CAS NO: 88908-87-6
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19038
• Product Categories: CARBOXYLICESTER
• Mol File: 88908-87-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-methylene-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-methylene-, methyl ester (9CI)(88908-87-6)
• EPA Substance Registry System: Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-methylene-, methyl ester (9CI)(88908-87-6)

Safety Data

• Hazardous Substances Data: 88908-87-6(Hazardous Substances Data)

Upstream product

• 61996-11-0 2-oxo-bicyclo[3.1.0]hexane-1-carboxylic acid methyl ester 
• 19493-09-5 Methylenetriphenylphosphorane 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 98758-86-2 (+/-)-α-cyclohexylidenemethyl-2-methylenebicyclo<3.1.0>hexane-1-methanol 
• 88908-94-5 (+/-)-(Z)-3-(2-cyclohexylidene-ethylidene)-t-5-methoxymethoxy-4-methylenecyclohexan-r-1-ol 
• 88908-93-4 (+/-)-2-hydroxy-2-<(3β-methoxymethoxy-2-methylenebicyclo<3.1.0>hexane)-1>ethylidenecyclohexane 
• 88908-95-6 (+/-)-(Z)-2-(3β,5α-dihydroxy-2-methylene-cyclohexylidene)ethylidenecyclohexane 
• 54676-97-0 cyclohexylidene-((Z)-2-methylene-cyclohexyliden)-ethane 
• 93601-58-2 (S)-Methoxy-phenyl-acetic acid (1S,5S)-2-methylene-bicyclo[3.1.0]hex-1-ylmethyl ester 
• 93490-19-8 (S)-Methoxy-phenyl-acetic acid (1R,5R)-2-methylene-bicyclo[3.1.0]hex-1-ylmethyl ester 
• 98758-87-3 (+/-)-α-cyclohexylidenemethyl-3-methoxymethoxy-2-methylenebicyclo<3.1.0>hexane-1-methanol 
• 67-97-0 5,6-trans-vitamin D₃ 
• 57651-83-9 trans-vitamin D₃ 
• 57651-82-8 3-epi-vitamin D₃ 
• 67-97-0 vitamin D₃ 

Relevant articles and documents

A General Method for the Synthesis of 3,5-Cyclovitamin D3 and Derivatives. A Stereoselective Synthesis of Vitamin D3

A stereoselective synthesis of vitamin D3 (1) was achieved via 3,5-cyclovitamin D3 (33) which was synthesized from the chiral aldehyde (3) and the vinyl bromide (27) derived from Grundmann's ketone (25). (+/-)-(Z)-5-(2-Cyclohexylidene-ethylidene)-4-methylenecyclohexane-r-1, t-3-diol (24) as a model compound of 1α-hydroxyvitamin D3 was also stereoselectively synthesized via the solvolysis of (+/-)-α-cyclohexylidenemethyl-3β-methoxymethoxy-2-methylenebicyclohexane-1-methanol (21) which was prepared from the aldehyde (12) and the organostannane (16).