889117-75-3

Upstream product

• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 59016-93-2 p-hydroxymethylphenylboronic acid 

Downstream Products

• 1093190-85-2 4-(4-morpholin-4-ylmethylbenzyl)benzoic acid methyl ester 
• 1400934-70-4 methyl 4-(4-(bromomethyl)benzyl)benzoate 
• 1400934-71-5 (4-(4-(bromomethyl)benzyl)phenyl)methanol 
• 1093190-86-3 4-(4-morpholin-4-ylmethylbenzyl)benzoic acid hydrochloride 
• 1093190-87-4 (2S,3R)-3-hydroxy-2-(4-(4-morpholin-4-ylmethylbenzyl)benzoylamino)butyric acid methyl ester 

Relevant academic research and scientific papers

Modular synthesis of bipyridinium oligomers and corresponding donor-acceptor oligorotaxanes with crown ethers

Donor-acceptor [4]- and [6]rotaxanes have been prepared from bipyridinium (BIPY2+) oligomers and 1,5-dinaphtho[38]crown-10 (DN38C10) by a threading-followed-by-stoppering protocol employing click chemistry. An efficient, straightforward route to the BIPY2+ oligomers has been developed that requires little to no chromatographic purification. Unlike most donor-acceptor oligorotaxanes that have been reported to date, 100% of the recognition sites on the dumbbells are occupied by rings.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.