88912-21-4

Usage

Uses

Used in Pharmaceutical Industry:
6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID is used as a key intermediate in the synthesis of pharmaceuticals for its potential to modulate biological pathways. It contributes to the development of new drugs with therapeutic applications.
Used in Agrochemical Industry:
6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID is utilized as a building block in the synthesis of agrochemicals, such as herbicides and pesticides, due to its ability to influence plant growth and control unwanted vegetation.
Used in Materials Science:
6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID serves as a precursor in the field of materials science, where it is involved in the creation of advanced materials with specific properties.
Used in Organic Chemistry:
As an intermediate in organic chemistry, 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID is employed in various chemical reactions to form a wide range of organic compounds for different applications.

InChI:InChI=1/C8H8ClNO3/c1-12-5-3-6(8(11)13-2)10-7(9)4-5/h3-4H,1-2H3

Upstream product

• 29681-43-4 methyl 4-methoxypicolinate 
• 86251-47-0 4-methoxy-2-(methoxycarbonyl)pyridine 1-oxide 
• 204378-41-6 methyl 6-chloro-4-methoxypicolinate 

Downstream Products

• 204378-21-2 N-[(2,3-Dichlorophenyl)sulfonyl]-6-chloro-4-methoxypyridine-2-carboxamide 
• 204378-27-8 N-[(2-Chlorophenyl)sulfonyl]-6-chloro-4-methoxypyridine-2-carboxamide 
• 204378-33-6 N-[(2,6-Difluorophenyl)sulfonyl]-6-chloro-4-methoxy-2-pyridinecarboxamide 
• 1122090-80-5 ethyl 6-chloro-4-methoxypicolinate 
• 1393486-28-6 6-chloro-4-methoxypyridine-2-carboxylic acid amide 
• 204378-29-0 N-[(2-Trifluoromethoxyphenyl)sulfonyl]-6-chloro-4-methoxy-2-pyridinecarboxamide 

Relevant academic research and scientific papers

CD38 INHIBITORS

One embodiment of the invention is a compound represented by Formula I: or a pharmaceutically acceptable salt thereof. The variables in Formula I are defined herein. Compounds of Formula I are CD38 inhibitors, which can be used to treat a disease or condition in a subject that benefits from an increase in NAD+ or to treat a mitochondrial disorder in a subject.

INHIBITORS OF HUMAN ATGL

The present invention relates to novel inhibitors of adipose triglyceride lipase (ATGL) having an improved inhibitory activity against human ATGL (hATGL) as well as pharmaceutical compositions comprising these inhibitors, and their therapeutic use, particularly in the treatment or prevention of a lipid metabolism disorder, including, e.g., obesity, non-alcoholic fatty liver disease, type 2 diabetes, insulin resistance, glucose intolerance, hypertriglyceridemia, metabolic syndrome, cardiac and skeletal muscle steatosis, congenital generalized lipodystrophy, familial partial lipodystrophy, acquired lipodystrophy syndrome, atherosclerosis, or heart failure.

N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide

A herbicide containing as the active ingredient an N-(henylsulfonyl)picolinamide derivative represented by general formula (I) wherein X reprcsents a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, a C1-4 haloalkoxy, a (C1-4 alkoxy)carbonyl, a [di(C1-4 alkyl)amino]sulfonyl, an [N—(C1-4 alkyl)-N—(C1-4 alkoxy)amino]sulfonyl, a (C1-4 alkylamino)sulfonyl, a C1-4 alkylthio, a C1-4 alkylsulfinyl, a C1-4 alkylsulfonyl, or nitro; n is an integer of 0 to 5; Y represets a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, C1-4 haloalkoxy, a C1-4 alkylthio, a C1-4 haloalkylthio, amino, a C1-4 alkylamino, a di(C1-4 alkyl)amino, a (C1-4 alkoxy) C1-4 alkyl, a (C1-4 alkylthio) C1-4 alkyl, or nitro; and m is an integer of 0 to 4. This active ingredient is synthesized by condensing a substituted picolinic acid with a substituted benzenesulfonamide under dehydration, or by reacting the phenyl ester of a substituted picolinic acid with a substituted benzenesulfonamide in the presence of a basic compound.