88912-21-4

Basic information

• Product Name: 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID;4-Methoxy-6-chloropicolinic acid;6-chloro-4-Methoxypicolinic acid
• CAS NO: 88912-21-4
• Molecular Formula: C₇H₆ClNO₃
• Molecular Weight: 187.58044
• Mol File: 88912-21-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 322.6 °C at 760 mmHg
• Flash Point: 148.9 °C
• Appearance: /
• Density: 1.430
• Vapor Pressure: 0.000276mmHg at 25°C
• Refractive Index: 1.521
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.15±0.10(Predicted)
• CAS DataBase Reference: 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID(88912-21-4)
• EPA Substance Registry System: 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID(88912-21-4)

Safety Data

• Hazardous Substances Data: 88912-21-4(Hazardous Substances Data)

Usage

General Description

6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID is a chemical compound with the molecular formula C7H6ClNO3. It is a derivative of pyridine and contains a chlorine atom, a methoxy group, and a carboxylic acid functional group. 6-CHLORO-4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in the development of new drugs and agrochemicals due to its ability to modulate biological pathways and its potential as a herbicide or pesticide. Additionally, this compound may have uses in the field of materials science and organic chemistry as a precursor or intermediate in chemical synthesis.

InChI:InChI=1/C8H8ClNO3/c1-12-5-3-6(8(11)13-2)10-7(9)4-5/h3-4H,1-2H3

Upstream product

• 29681-43-4 methyl 4-methoxypicolinate 
• 86251-47-0 4-methoxy-2-(methoxycarbonyl)pyridine 1-oxide 
• 204378-41-6 methyl 6-chloro-4-methoxypicolinate 

Downstream Products

• 204378-33-6 N-[(2,6-Difluorophenyl)sulfonyl]-6-chloro-4-methoxy-2-pyridinecarboxamide 
• 1393486-28-6 6-chloro-4-methoxypyridine-2-carboxylic acid amide 
• 1122090-80-5 ethyl 6-chloro-4-methoxypicolinate 
• 204378-27-8 N-[(2-Chlorophenyl)sulfonyl]-6-chloro-4-methoxypyridine-2-carboxamide 
• 204378-29-0 N-[(2-Trifluoromethoxyphenyl)sulfonyl]-6-chloro-4-methoxy-2-pyridinecarboxamide 
• 204378-21-2 N-[(2,3-Dichlorophenyl)sulfonyl]-6-chloro-4-methoxypyridine-2-carboxamide 

Relevant articles and documents

CD38 INHIBITORS

One embodiment of the invention is a compound represented by Formula I: or a pharmaceutically acceptable salt thereof. The variables in Formula I are defined herein. Compounds of Formula I are CD38 inhibitors, which can be used to treat a disease or condition in a subject that benefits from an increase in NAD+ or to treat a mitochondrial disorder in a subject.

N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide

A herbicide containing as the active ingredient an N-(henylsulfonyl)picolinamide derivative represented by general formula (I) wherein X reprcsents a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, a C1-4 haloalkoxy, a (C1-4 alkoxy)carbonyl, a [di(C1-4 alkyl)amino]sulfonyl, an [N—(C1-4 alkyl)-N—(C1-4 alkoxy)amino]sulfonyl, a (C1-4 alkylamino)sulfonyl, a C1-4 alkylthio, a C1-4 alkylsulfinyl, a C1-4 alkylsulfonyl, or nitro; n is an integer of 0 to 5; Y represets a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, C1-4 haloalkoxy, a C1-4 alkylthio, a C1-4 haloalkylthio, amino, a C1-4 alkylamino, a di(C1-4 alkyl)amino, a (C1-4 alkoxy) C1-4 alkyl, a (C1-4 alkylthio) C1-4 alkyl, or nitro; and m is an integer of 0 to 4. This active ingredient is synthesized by condensing a substituted picolinic acid with a substituted benzenesulfonamide under dehydration, or by reacting the phenyl ester of a substituted picolinic acid with a substituted benzenesulfonamide in the presence of a basic compound.