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(3S,4S)-4-(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)piperidine, also known as Lufuradom, is a fluorinated piperidine derivative with a unique molecular structure that features a piperidine ring with a fluorophenyl and a trifluoromethylphenyl group attached to it. This structure endows Lufuradom with specific pharmacological properties, making it a selective antagonist for the kappa opioid receptor.

889126-32-3

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889126-32-3 Usage

Uses

Used in Pharmaceutical Industry:
Lufuradom is used as a therapeutic agent for the treatment of chronic pain and addiction. Its selective antagonism of the kappa opioid receptor suggests potential benefits in managing pain and addiction without the typical side effects associated with other opioid receptor antagonists.
Used in Research and Development:
Lufuradom is utilized in preclinical models to study its pharmacological effects and therapeutic potential. Further research is needed to better understand its efficacy, safety, and possible side effects, which will inform its development as a novel treatment option for chronic pain and addiction management.

Check Digit Verification of cas no

The CAS Registry Mumber 889126-32-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,1,2 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 889126-32:
(8*8)+(7*8)+(6*9)+(5*1)+(4*2)+(3*6)+(2*3)+(1*2)=213
213 % 10 = 3
So 889126-32-3 is a valid CAS Registry Number.

889126-32-3Downstream Products

889126-32-3Relevant academic research and scientific papers

CYCLOALKYL KETO PIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS

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Page/Page column 21, (2008/06/13)

The present invention is directed to certain piperidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations co

CYCLOALKYL PIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS

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Page/Page column 21-22, (2010/11/08)

The present invention is directed to certain piperidine compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations co

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