889127-22-4Relevant academic research and scientific papers
Palladium-catalyzed regio-, diastereo-, and enantioselective allylation of nitroalkanes with monosubstituted allylic substrates
Yang, Xiao-Fei,Yu, Wei-Hua,Ding, Chang-Hua,Ding, Qiu-Ping,Wan, Shi-Li,Hou, Xue-Long,Dai, Li-Xin,Wang, Pin-Jie
, p. 6503 - 6509 (2013/07/26)
Pd-catalyzed asymmetric allylic alkylation of nitroalkanes and monosubstituted allylic substrates was performed to afford products with two adjacent chiral centers and with excellent regio-, diastereo-, and enantioselectivities. The usefulness of the protocol in organic synthesis was demonstrated by transformation of the product to an optically active homoallylamine, a 2,3-disubstituted tetrahydropyridine, and an α,β-disubstituted amino acid derivative.
