889130-08-9

Basic information

• Product Name: ethyl (R)-3-(dimethylphenylsilyl)butanoate
• Synonyms: ethyl (R)-3-(dimethylphenylsilyl)butanoate
• CAS NO: 889130-08-9
• Molecular Weight: 250.413
• Mol File: 889130-08-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl (R)-3-(dimethylphenylsilyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (R)-3-(dimethylphenylsilyl)butanoate(889130-08-9)
• EPA Substance Registry System: ethyl (R)-3-(dimethylphenylsilyl)butanoate(889130-08-9)

Safety Data

• Hazardous Substances Data: 889130-08-9(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 193006-90-5 ethyl (Z)-3-(dimethyl(phenyl)silyl)-2-butenoate 
• 193006-89-2 ethyl (E)-3-(dimethyl(phenyl)silyl)-2-butenoate 
• 56583-95-0 1-(dimethyl(phenyl)silyl)ethanone 

Downstream Products

• 128474-83-9 (R)-3-(dimethyl(phenyl)silyl)butanoyl chloride 
• 164203-15-0 (R)-3-(dimethyl(phenyl)silyl)butanoic acid 

Relevant articles and documents

A conjugate reduction pathway to chiral silanes using CuH

Experimental details concerning asymmetric 1,4-reduction of β-silylated-β,β-disubstituted enoates catalyzed by CuH are described. High yields and enantiomeric excesses are to be expected when Solvias' JOSIPHOS bis-phosphine PPF-P(t-Bu)2 is used as a non-racemic ligand. Georg Thieme Verlag Stuttgart.

Chiral silanes via asymmetric hydrosilylation with catalytic CuH

CuH-catalyzed asymmetric conjugate reduction of β-silyl-α, β-unsaturated esters has been developed. Using PMHS as a stoichiometric source of hydride and in situ generated CuH ligated by Solvias' JOSIPHOS analogue PPF-P(t-Bu)2 leads to highly enantioselective 1,4-reductions.