88917-11-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Chlorothiazole-5-sulfonyl chloride is used as a key intermediate in the synthesis of thiazole-based pharmaceuticals and agrochemicals. Its ability to introduce the sulfonyl chloride group aids in the development of new therapeutic agents and pesticides.
Used in Production of Dyes and Fine Chemicals:
In the chemical industry, 2-Chlorothiazole-5-sulfonyl chloride is utilized for the production of dyes and other fine chemicals, where its reactivity is harnessed to create a variety of specialty compounds.
Safety Considerations:
It is crucial to handle 2-chlorothiazole-5-sulfonyl chloride with care due to its classification as a hazardous material. Exposure can result in skin, eye, and respiratory system irritation, necessitating proper safety measures during its use and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 88917-11-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,1 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 88917-11:
(7*8)+(6*8)+(5*9)+(4*1)+(3*7)+(2*1)+(1*1)=177
177 % 10 = 7
So 88917-11-7 is a valid CAS Registry Number.
88917-11-7Relevant academic research and scientific papers
Acetylenyl-pyrazolo-pyrimidine derivatives
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Page/Page column 27, (2008/06/13)
The present invention relates to compounds of formula (I): wherein R1 to R3, A, M, L, E, G, and J are as defined in the description and claims. The invention also relates to a process for the manufacture of such compounds, pharmaceutical compositions containing them, and methods for treating CNS disorders.
Acyl sulfonamide anti-proliferatives. Part 2: Activity of heterocyclic sulfonamide derivatives
Mader, Mary M.,Shih, Chuan,Considine, Eileen,De Dios, Alfonso,Grossman, Cora Sue,Hipskind, Philip A.,Lin, Ho-Shen,Lobb, Karen L.,Lopez, Beatriz,Lopez, Jose E.,Cabrejas, Luisa M. Martin,Richett, Michael E.,White, Wesley T.,Cheung, Yiu-Yin,Huang, Zhongping,Reilly, John E.,Dinn, Sean R.
, p. 617 - 620 (2007/10/03)
The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116 tumor cells in a soft agar diffusion assay.
