88931-02-6

Upstream product

• 97616-62-1 (+/-)-4-acetoxy-2-(2-cyclohexylidene-seqcis-ethylidene)-cyclohexanone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 98758-86-2 (+/-)-α-cyclohexylidenemethyl-2-methylenebicyclo<3.1.0>hexane-1-methanol 
• 1121-49-9 bromomethylenecyclohexane 
• 97616-62-1 (+/-)-4-acetoxy-2-(2-cyclohexylidene-seqtrans-ethylidene)-cyclohexanone 
• 52183-68-3 1-dibromomethyl-1-cyclohexanol 

Relevant academic research and scientific papers

A General Method for the Synthesis of 3,5-Cyclovitamin D3 and Derivatives. A Stereoselective Synthesis of Vitamin D3

A stereoselective synthesis of vitamin D3 (1) was achieved via 3,5-cyclovitamin D3 (33) which was synthesized from the chiral aldehyde (3) and the vinyl bromide (27) derived from Grundmann's ketone (25). (+/-)-(Z)-5-(2-Cyclohexylidene-ethylidene)-4-methylenecyclohexane-r-1, t-3-diol (24) as a model compound of 1α-hydroxyvitamin D3 was also stereoselectively synthesized via the solvolysis of (+/-)-α-cyclohexylidenemethyl-3β-methoxymethoxy-2-methylenebicyclohexane-1-methanol (21) which was prepared from the aldehyde (12) and the organostannane (16).