88931-75-3

Basic information

• Product Name: Cyclopentaneacetic acid, 1,1-dimethylethyl ester
• Synonyms: tert-butyl cyclopentylacetate;Cyclopentaneacetic acid,1,1-dimethylethyl ester
• CAS NO: 88931-75-3
• Molecular Formula: C11H20O2
• Molecular Weight: 184.279
• Mol File: 88931-75-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclopentaneacetic acid, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentaneacetic acid, 1,1-dimethylethyl ester(88931-75-3)
• EPA Substance Registry System: Cyclopentaneacetic acid, 1,1-dimethylethyl ester(88931-75-3)

Safety Data

• Hazardous Substances Data: 88931-75-3(Hazardous Substances Data)

Upstream product

• 1122-99-2 2-cyclopentylacetyl chloride 
• 865-47-4 potassium tert-butylate 
• 1123-00-8 2-cyclopentylacetic acid 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 88931-70-8 (E)-7-Iodo-hept-2-enoic acid tert-butyl ester 
• 117471-88-2 tert-butyl (E)-7-iodohept-2-enoate 

Downstream Products

• 1380605-06-0 (+/-)-tert-butyl cyclopentyl(4-fluorophenyl)acetate 
• 1082507-58-1 (+/-)-Cyclopentyl(4-fluorophenyl)acetic acid 

Relevant articles and documents

Substituted 1-benzylcycloalkylcarboxylic acids and the use thereof

The present application relates to novel substituted 1-benzylcycloalkylcarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

Conjugate Addition Reactions Mediated by Samarium(II) Iodide

Samarium(II) iodide in conjunction with a catalytic low-valent transition metal species has been employed to promote the conjugate addition reaction of primary and secondary alkyl halides onto α,β-unsaturated esters and amides. The method has been determined to be quite general and hence has been extended to the cyclization reactions of alkyl halides onto α,β-unsaturated lactones, lactams, and nitriles. The cyclization reactions described herein provide a very general approach to the synthesis of functionalized carbocycles from simple acyclic precursors with excellent diastereoselectivity and under very mild reaction conditions.