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1-(4-(Benzyloxy)-6-methyl-1H-indol-2-yl)ethanol, also known as AM630, is a chemical compound that serves as a potent and selective antagonist of the CB2 cannabinoid receptor. This means it binds to and blocks the activity of the CB2 receptor, which is involved in various physiological and pathological processes. With its unique chemical structure and pharmacological properties, AM630 is a valuable tool for studying cannabinoid receptors and developing new medications.

889674-97-9

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889674-97-9 Usage

Uses

Used in Pharmaceutical Research:
1-(4-(Benzyloxy)-6-methyl-1H-indol-2-yl)ethanol is used as a research compound for investigating the role of the endocannabinoid system in physiological and pathological processes. Its application aids in understanding how the CB2 receptor can be targeted for therapeutic purposes.
Used in Pain Management:
In the medical field, 1-(4-(Benzyloxy)-6-methyl-1H-indol-2-yl)ethanol is used as a potential therapeutic agent for managing pain. By blocking the CB2 receptor, it may help in alleviating pain associated with various conditions.
Used in Inflammation Treatment:
AM630 is also used as an anti-inflammatory agent, as modulation of the CB2 receptor can help in reducing inflammation, which is a common factor in many diseases and disorders.
Used in Drug Addiction Treatment:
1-(4-(Benzyloxy)-6-methyl-1H-indol-2-yl)ethanol is used as a potential therapeutic agent in the treatment of drug addiction. Its action as a CB2 receptor antagonist may help in reducing the rewarding effects of addictive substances, thus aiding in the recovery process.
Used in Neurodegenerative Disease Research:
In the field of neuroscience, AM630 is used as a research tool to study the involvement of the endocannabinoid system in neurodegenerative diseases such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease. Understanding the role of CB2 receptors in these conditions can lead to the development of novel therapeutic strategies.
Used in Immunological Research:
1-(4-(Benzyloxy)-6-methyl-1H-indol-2-yl)ethanol is used in immunological research to explore the role of the CB2 receptor in immune system regulation. This can help in developing new treatments for immune-related disorders and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 889674-97-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,6,7 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 889674-97:
(8*8)+(7*8)+(6*9)+(5*6)+(4*7)+(3*4)+(2*9)+(1*7)=269
269 % 10 = 9
So 889674-97-9 is a valid CAS Registry Number.

889674-97-9Relevant academic research and scientific papers

The first potent inhibitor of mammalian group X secreted phospholipase A2: Elucidation of sites for enhanced binding

Smart, Brian P.,Oslund, Rob C.,Walsh, Laura A.,Gelb, Michael H.

, p. 2858 - 2860 (2007/10/03)

Using the X-ray structure of human group X secreted phospholipase A 2 (hGX), we carried out structure-based design of indole-based inhibitors and prepared the compounds using a new synthetic route. The most potent compound inhibited hGX and the mouse orthologue with an IC50 of 75 nM. This compound is the most potent hGX inhibitor reported to date and was also found to inhibit a subset of the other mouse and human SPLA 2S.

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