889679-04-3

Usage

General Description

1,8-Naphthyridine-2,7-diamine, N,N-di-2-pyridinyl- (9CI) is a chemical compound that is also known as dipyridamole. It belongs to the class of naphthyridine derivatives and is often used as an antiplatelet medication to prevent blood clots. It works by inhibiting the breakdown of blood clots, which lowers the risk of stroke and heart attack. Dipyridamole is also used in combination with other medications to treat conditions such as coronary artery disease and angina. It is typically administered orally or through injection, and its use should be closely monitored by a healthcare professional to avoid potential side effects and drug interactions.

Upstream product

• 504-29-0 2-aminopyridine 
• 55243-02-2 2,7-dichloro-1,8-naphthyridine 

Relevant academic research and scientific papers

Novel linear hexanuclear cobalt string complexes (Co6 12+) and one-electron reduction products (Co6 11+) supported by four bpyany2- ligands

The new ligand, 2,7-bis(α-pyridylamino)-1,8-naphthyridine (H 2bpyany), was synthesized by the reaction of 2,7-dichloro-1,8- naphthyridine with 2-aminopyridine in the presence of t-BuOK under palladium(0)-catalyzed conditions. The preparation and characterization of novel hexacobalt string complexes, [Co6(6-bpyany) 4(NCS)2](PF6)n (n = 1 (1); n = 2 (2)) and [Co6(6-bpyany)4(OTf) 2](OTf)n (n = 2 (3); n = 1 (4)) are presented. The crystal structures for compounds 1-4 have been determined by X-ray crystallography. Compounds 1 and 4 have the Co611+ configurations and are air-stable. Compounds 2 and 3 with Co612+ configurations are structurally similar to 1 and 4, respectively. The electrochemistry of 1 displays four redox couples at E1/2 = -0.55, +0.38, +0.91, and +1.18 V (vs. Ag/AgCl). The magnetic data show that compounds 1 and 4 are in a spin state of S = 1/2, and 2 and 3 in a spin state of S = 1. The results of the EHMO calculations on compounds 1 and 2 are in agreement with their magnetic measurements. The Royal Society of Chemistry 2006.