88980-54-5

Basic information

• Product Name: (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one
• CAS NO: 88980-54-5
• Molecular Formula: C₂₇H₄₄O₇
• Molecular Weight: 480.6341
• Mol File: 88980-54-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 713.2°C at 760 mmHg
• Flash Point: 399.1°C
• Density: 1.28g/cm³
• Vapor Pressure: 1.69E-23mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one(88980-54-5)
• EPA Substance Registry System: (2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one(88980-54-5)

Safety Data

• Hazardous Substances Data: 88980-54-5(Hazardous Substances Data)

Usage

General Description

The chemical "(2beta,3beta,5beta,22R)-2,3,14,20,22,26-hexahydroxycholest-7-en-6-one" is a steroidal compound with a distinct hexahydroxycholesterol structure. It is a derivative of cholesterol and is characterized by the presence of hydroxyl groups at the 2, 3, 5, 14, 20, and 22 positions. The compound also contains a double bond at the 7th position and a ketone group at the 6th position. This chemical has potential biological activity and may play a role in various physiological processes. Its structure and properties make it an important molecule of interest in the field of biochemistry and pharmaceutical research.

Upstream product

• 13408-48-5 ponasterone A 

Downstream Products

• 114752-28-2 26-iodoponasterone A 

Relevant articles and documents

ECDYSTEROID METABOLISM IN A CRAB: CARCINUS MAENAS L.

Ponasterone A (25-deoxy-20-hydroxyecdysone) and 20-hydroxyecdysone were the major ecdysteroids detected in crab hemolymph, although some ecdysone was also present.The metabolism of ponasterone A was examined in intermolt and premolt crabs either by injecting the radiolabeled hormone or by incubating tissues in its presence.Metabolites were extracted from the surrounding seawater and from tissues and separated by high-performance liquid chromatography.Ponasterone A metabolism proceeds through (1) C-25 and C-26 hydroxylation, followed by formation of inactivation products via oxidation of the terminal alcoholic group to a carboxylic residue, (2) conjugation, (3) binding to very polar compounds and (4) side-chain scission.The conversion of ponasterone A into 20-hydroxyecdysone, inokosterone (25-deoxy-20,26-dihydroxyecdysone), 20,26-dihydroxyecdysone and ecdysonoic acids, as well as the formation of conjugates and of very polar compounds, occurs in various tissues.These metabolites were excreted by both intermolt and premolt crabs.