88981-39-9

Upstream product

• 88981-37-7 (2S,4R)-1-(benzyloxy)-4,5-epoxy-2-hydroxy-pentane 
• 109987-43-1 (2R,4R)-1-Benzyloxy-hept-6-ene-2,4-diol 
• 1536054-05-3 (4S,6S)-7-(benzyloxy)-6-hydroxyhept-1-en-4-yl tert-butyl carbonate 
• 1536054-01-9 tert-butyl (S)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)pent-4-en-2-yl carbonate 
• 87318-97-6 (2S)-1-[(4S)-2,2-dimethyl[1,3]dioxolan-4-yl]pent-4-en-2-ol 
• 88981-35-5 (2S)-1-(benzyloxy)pent-4-en-2-ol 
• 88981-38-8 2S,4S-(-)-benzyl-2,4-dihydroxyhept-6-enyl ether 
• 88981-36-6 (4R,6S)-4-Benzyloxymethyl-6-iodomethyl-[1,3]dioxan-2-one 
• 2930-05-4 (S)-benzyl glycidyl ether 

Downstream Products

• 88981-41-3 (S)-1-((4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-pent-4-en-2-ol 
• 1536054-10-0 (2S,5S)-1-((4S,6S)-6-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)-5-((2S,4S)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl)-4-methylenehexan-2-ol 
• 1536054-15-5 (2R,5R)-6-((4R,6S)-6-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxan-4-yl)-5-((tert-butyldimethylsilyl)oxy)-2-((2S,4S)-2-(4-methoxyphenyl)-1,3-dioxan-4-yl)hexan-3-one 
• 109987-48-6 (S)-1-((4R,6R)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-3-[1,3]dithian-2-yl-propan-2-ol 
• 128260-63-9 C₅₀H₉₂O₉S₂Si₂ 
• 128260-64-0 (2S,4R)-1-((4R,6R)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-5-{(4S,6R)-6-[(2R,5S,6S)-6-(tert-butyl-dimethyl-silanyloxy)-5,7-dimethyl-2-(2-trimethylsilanyl-ethoxymethoxy)-octyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-pentane-2,4-diol 
• 128260-59-3 (4R,6R)-4-Benzyloxymethyl-6-[(S)-3-{2-[(1R,2S)-2-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-butyl]-[1,3]dithian-2-yl}-2-(2-trimethylsilanyl-ethoxymethoxy)-propyl]-2,2-dimethyl-[1,3]dioxane 
• 128260-58-2 (S)-1-((4R,6R)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-3-{2-[(1R,2S)-2-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-butyl]-[1,3]dithian-2-yl}-propan-2-ol 
• 88981-40-2 (4R,6R)-4-Benzyloxymethyl-2,2-dimethyl-6-(S)-1-oxiranylmethyl-[1,3]dioxane 
• 88981-40-2 (4S,6S)-4-((benzyloxy)methyl)-2,2-dimethyl-6-((R)-oxiran-2-ylmethyl)-1,3-dioxane 

Relevant academic research and scientific papers

Asymmetric alcohol C-H allylation and syn -Crotylation: C9-C20 of tetrafibricin

The C9-C20 segment of the fibrinogen receptor inhibitor tetrafibricin was prepared in 10 steps (longest linear sequence). Ruthenium catalyzed enantioselective syn-crotylation is used to construct C9-C13. Iridium catalyzed asymmetric alcohol C-H allylation

PROGRESS TOWARD ROFLAMYCOIN; SYNTHESIS OF THE C-12 TO C-35 SECTION IN HOMOCHIRAL FORM

A 24 carbon fragment containing 11 chiral centers has been prepared in optically pure form en route to the polyene macrolide roflamycoin.

A Reiterative Route to Chiral all-syn-1,3-Polyols

An efficient, enantioselective procedure for obtaining syn-1,3-polyols is described.The method relies on a reiterative two-step protocol involving stereoselective homoallylic alcohol epoxidation followed by ring opening via a higher order, mixed organocup