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5-(Methylsulfonyl)-4H-1,2,4-triazol-3-amine, also known as tadalafil, is a phosphodiesterase inhibitor with the molecular formula C9H9N5O2S. It is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE-5), which is responsible for the degradation of cGMP in the corpus cavernosum.

88982-32-5

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88982-32-5 Usage

Uses

Used in Pharmaceutical Industry:
5-(Methylsulfonyl)-4H-1,2,4-triazol-3-amine is used as a treatment for erectile dysfunction and benign prostatic hyperplasia. It works by increasing blood flow to the penis during sexual stimulation, leading to improved erectile function.
Used in Sexual Health:
5-(Methylsulfonyl)-4H-1,2,4-triazol-3-amine is used as a phosphodiesterase inhibitor to enhance erectile function by inhibiting the degradation of cGMP in the corpus cavernosum.
It is important to consult a healthcare professional before using 5-(Methylsulfonyl)-4H-1,2,4-triazol-3-amine, as it may interact with certain medications and have potential side effects. It is available in various formulations, including tablets, and is typically taken as needed before sexual activity.

Check Digit Verification of cas no

The CAS Registry Mumber 88982-32-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,8 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 88982-32:
(7*8)+(6*8)+(5*9)+(4*8)+(3*2)+(2*3)+(1*2)=195
195 % 10 = 5
So 88982-32-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H6N4O2S/c1-10(8,9)3-5-2(4)6-7-3/h1H3,(H3,4,5,6,7)

88982-32-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methylsulfonyl-1H-1,2,4-triazol-3-amine

1.2 Other means of identification

Product number -
Other names 3(5)-amino-5(3)-methylsulfonyl-1,2,4-triazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88982-32-5 SDS

88982-32-5Downstream Products

88982-32-5Relevant academic research and scientific papers

Synthesis of novel derivatives of 3(5)-alkylsulfonyl-1,2,4-triazoles

Tolstyakov,Pevzner,Tselinskii

, p. 1458 - 1465 (2007/10/03)

The feasibility of preparing novel 1,2,4-triazole derivatives bearing alkylsulfonyl and other functional groups on the ring carbon atom has been demonstrated. The syntheses are carried out via transformation of the amino group of 3(5)-alkylsulfonyl-5(3)-amino-1,2,4-triazoles into other functional groups.

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