889852-07-7

Upstream product

• 7035-09-8 5-chloro-2-methoxybenzaldehyde 
• 889855-59-8 (2E)-2-{[(tert-butoxycarbonyl)amino]methyl}-3-(5-chloro-2-methoxyphenyl)-2-propenoic acid 
• 889855-40-7 (2E)-2-(aminomethyl)-3-(5-chloro-2-methoxyphenyl)-2-propenoic acid 
• 945013-25-2 C₁₅H₁₇ClO₅ 

Downstream Products

• 889852-53-3 6-(5-chloro-2-methoxybenzyl)-4-[(4-chlorophenyl)sulfonyl]-1,4-diazepan-2,5-dione 

Relevant academic research and scientific papers

Identification of 6-substituted 4-arylsulfonyl-1,4-diazepane-2,5-diones as a novel scaffold for human chymase inhibitors

A novel series of 6-substituted 4-sulfonyl-1,4-diazepane-2,5-diones were designed, synthesized and evaluated as human chymase inhibitors. Structure-activity relationship studies led to the identification of a potent inhibitor, (6S)-6-(5-chloro-2-methoxybe