88991-22-4

Basic information

• Product Name: 2-Propenoic acid, 2-(benzoylamino)-3-(3-thienyl)-, (Z)-
• CAS NO: 88991-22-4
• Molecular Formula: C14H11NO3S
• Molecular Weight: 273.312
• Mol File: 88991-22-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(benzoylamino)-3-(3-thienyl)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(benzoylamino)-3-(3-thienyl)-, (Z)-(88991-22-4)
• EPA Substance Registry System: 2-Propenoic acid, 2-(benzoylamino)-3-(3-thienyl)-, (Z)-(88991-22-4)

Safety Data

• Hazardous Substances Data: 88991-22-4(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 498-62-4 3-thiophene carboxaldehyde 
• 88991-46-2 (Z)-2-Phenyl-5-oxo-4-(3-thienylmethylene)-4,5-dihydro-1,3-oxazole 

Downstream Products

• 22574-47-6 D-2-amino-3-thiophen-3-yl-propionic acid 
• 89921-39-1 (R)-N-benzoyl-3-(3-thienyl)-alanine 

Relevant articles and documents

UNUSUAL AMINO ACIDS. IV. ASYMMETRIC SYNTHESIS OF THIENYLALANINES

(Z)-2-N-Acylamino-3-thienyl-acrylic acids and thei esters were prepared by known procedures and hydrogenated to the corresponding optically active 2-N-acetyl(or benzoyl)-3-(2- or 3-thienyl)-alanines with optically yields up to 90percent using the rhodium complexes of 'PROPRAPHOS" 6a,b and O,N-bis(diphenylphosphino)-2-exo-hydroxy,3-endo-methylamino-norbornane 6c as chiral catalysts.Recrystallization and deacylation of the obtained amino acid derivatives yields the optically pure hydrochlorides of the thienylalanines as the free amino acids.