89-29-2

Basic information

• Product Name: 3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE
• Synonyms: sulfamidopyrazolone;3-METHYL-1-(3'-SULFAMOYLPHENYL)-5-PYRAZOLONE;3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE;1-(3'-SULFAMOYL)-3-METHYL-5-PYRAZOLONE;1-(3-sulfoamidophenyl)-3-Methyl-5-pyrazolone;m-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzenesulphonamide;1-(3-Sulfaminephenyl)-3-Methyl-5-Pyrazolone;3-(3-methyl-5-oxo-4,5-dihydropyrazol-1-yl)benzenesulfonamide
• CAS NO: 89-29-2
• Molecular Formula: C₁₀H₁₁N₃O₃S
• Molecular Weight: 253.28
• EINECS: 201-895-2
• Product Categories: Intermediates of Dyes and Pigments;Building Blocks;Heterocyclic Building Blocks;Pyrazoles
• Mol File: 89-29-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 202-206 °C(lit.)
• Boiling Point: 541.6 °C at 760 mmHg
• Flash Point: 281.4 °C
• Appearance: /
• Density: 1.52 g/cm³
• Vapor Pressure: 8.52E-12mmHg at 25°C
• Refractive Index: 1.684
• PKA: 10.04±0.60(Predicted)
• CAS DataBase Reference: 3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE(89-29-2)
• EPA Substance Registry System: 3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE(89-29-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 1
• HazardClass: IRRITANT
• Hazardous Substances Data: 89-29-2(Hazardous Substances Data)

Usage

General Description

3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE is a synthetic chemical compound that belongs to the pyrazolone group. It is commonly used as a dye and a colorant in various industries, including textiles, paints, and printing inks. This chemical has a sulfur-containing sulfoamidophenyl group, which gives it its vibrant and stable color properties. It is also known for its excellent lightfastness and heat stability, making it suitable for a wide range of applications. Additionally, 3-METHYL-1-(3'-SULFOAMIDOPHENYL)-5-PYRAZOLONE is often used as a pH indicator and in medical diagnostic tests due to its ability to change color in response to changes in acidity or alkalinity.

InChI:InChI=1/C10H11N3O3S/c1-7-5-10(14)13(12-7)8-3-2-4-9(6-8)17(11,15)16/h2-4,6H,5H2,1H3,(H2,11,15,16)

Upstream product

• 131774-72-6 3-hydrazino-benzenesulfonic acid amide 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 1203500-89-3 C₁₁H₁₁N₃O₄S 
• 1236792-62-3 C₁₁H₁₁N₃O₄S 
• 184707-71-9 3-(4-(2-ethylanilinomethylenaminomethylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-benzolsulfonamide 
• 578-54-1 ortho-ethylaniline 

Relevant articles and documents

Copper/Persulfate-Promoted Oxidative Decarboxylative C?H Acylation of Pyrazolones with α-Oxocarboxylic Acids: Direct Access to 4-Acylpyrazolones under Mild Conditions

A facile and efficient oxidative C?H acylation of N-substituted pyrazolones using α-oxocarboxylic acids as an acyl group source was developed. A combination of Cu(OAc)2 and K2S2O8 enables the reaction to proceed smoothly under air and provides a wide array of 4-acylpyrazolone products in moderate to excellent yields. The mechanism of this transformation is believed to proceed via a copper-induced decarboxylation to form the acyl-copper species. This method provides a convenient and useful route for a direct installation of an acyl moiety into bioactive pyrazolone derivatives, which can be further utilized in many applications. (Figure presented.).