890048-80-3Relevant academic research and scientific papers
Enantioselective and diastereoselective syntheses of cyanohydrin carbonates
Belokon', Yuri N.,Clegg, William,Harrington, Ross W.,Ishibashi, Eisuke,Nomura, Hiroshi,North, Michael
, p. 9724 - 9740 (2007)
A new and general synthesis of alkyl cyanoformates is presented starting from the appropriate alcohol and oxalyl chloride. This is used to prepare enantiomerically pure cyanoformates from enantiomerically pure primary and secondary alcohols. Optimal condi
Cyanide ion cocatalysis in Ti(salen) catalysed asymmetric cyanohydrin carbonate synthesis
Belokon, Yuri N.,Ishibashi, Eisuke,Nomura, Hiroshi,North, Michael
, p. 1775 - 1777 (2008/09/16)
In the presence of potassium cyanide or the potassium cyanide/18-crown-6 complex as a cocatalyst, 1-2 mol% of titanium(salen) complex 1 catalyses the asymmetric addition of achiral cyanoformates to aldehydes, giving cyanohydrin carbonates with high enanti
