89006-96-2

Usage

General Description

5-isopropyl-1,3-oxazole-4-carboxylic acid, also known as SALTDATA: FREE, is a chemical compound with a molecular formula C8H11NO3. It is a derivative of oxazole and carboxylic acid, and is characterized by its isopropyl group. 5-isopropyl-1,3-oxazole-4-carboxylic acid(SALTDATA: FREE) is commonly used in organic synthesis and pharmaceutical research, and may have potential applications in the development of new drugs or medicines. Its properties and potential uses make it an important compound in the field of medicinal chemistry and drug discovery.

Upstream product

• 72030-85-4 4-methoxycarbonyl-5-(1-methylethyl)-1,3-oxazole 
• 32968-46-0 ethyl 5-isopropyl-1,3-oxazole-4-carboxylate 

Downstream Products

• 21419-25-0 1-amino-3-methyl-2-butanone monohydrochloride 

Relevant academic research and scientific papers

Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks

An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.

BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

NOVEL PHARMACEUTICALS

The present invention relates to immune response modifiers of formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.

Alkyloxazolylacetic acid derivative for the treatment of hyperlipidemia

A alkyloxazolylacetic acid derivative of the formula: STR1 wherein Ring A is phenyl or halogenophenyl, R1 is lower alkyl of one to 5 carbon atoms and R2 is hydrogen or lower alkyl of one to 3 carbon atoms. The compound (I) is useful