890080-03-2

Basic information

• Product Name: (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid
• Synonyms: (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid
• CAS NO: 890080-03-2
• Molecular Weight: 621.754
• Mol File: 890080-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid(890080-03-2)
• EPA Substance Registry System: (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid(890080-03-2)

Safety Data

• Hazardous Substances Data: 890080-03-2(Hazardous Substances Data)

Upstream product

• 189940-64-5 [6-Benzyloxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanone 
• 890080-02-1 (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetic acid ethyl ester 

Downstream Products

• 890080-04-3 (4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetyl chloride 
• 890080-05-4 [[2-(4-{6-benzyloxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenoxy)-acetylamino]-(diethoxy-phosphoryl)-methyl]-phosphonic acid diethyl ester 

Relevant articles and documents

Synthesis of novel bone-targeted agents for treatment of osteoporosis

Novel bone-targeted agents have been designed and synthesized by the combination of raloxifene and bisphosphonates. The anti-osteoporosis effect has been evaluated by bone mineral density (BMD) obtained from ovariectomized (OVX) mice in vivo. The results indicate that the compounds 8 and 9 not only prevent ovariectomy induced loss of bone but also enhance BMD to 7.09 and 12.59% compared to sham-operated control, respectively.