890124-18-2Relevant academic research and scientific papers
Design, synthesis, and evaluation of novel kazusamycin A derivatives as potent antitumor agents
Ando, Ryoichi,Amano, Yusaku,Nakamura, Hideo,Arai, Noriyoshi,Kuwajima, Isao
, p. 3315 - 3318 (2007/10/03)
Novel kazusamycin A derivatives were designed in the viewpoint of decrease of reactivity at the α,β-unsaturated δ-lactone moiety against Michael-type addition. Although 25-30 steps were required for the synthesis of each compound, their syntheses were ach
