89013-87-6

Basic information

• Product Name: 1-methyl-4-[5-(4'-methoxyphenyl)-2-oxazolyl]pyridinium p-toluenesulfonate
• CAS NO: 89013-87-6
• Molecular Weight: 438.504
• Mol File: 89013-87-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-4-[5-(4'-methoxyphenyl)-2-oxazolyl]pyridinium p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-[5-(4'-methoxyphenyl)-2-oxazolyl]pyridinium p-toluenesulfonate(89013-87-6)
• EPA Substance Registry System: 1-methyl-4-[5-(4'-methoxyphenyl)-2-oxazolyl]pyridinium p-toluenesulfonate(89013-87-6)

Safety Data

• Hazardous Substances Data: 89013-87-6(Hazardous Substances Data)

Upstream product

• 96753-33-2 2-(4-pyridyl)-5-(4-methoxyphenyl)-oxazole 
• 80-48-8 methyl p-toluene sulfonate 
• 55-22-1 pyridine-4-carboxylic acid 
• 3883-94-1 2-amino-4'-methoxyacetophenone hydrochloride 
• 40513-43-7 2-amino-1-(4-methoxy-phenyl)-ethanone 

Relevant articles and documents

Photophysics of a series of efficient fluorescent pH probes for dual-emission-wavelength measurements in aqueous solutions

This paper evaluates the 5-aryl-2-pyridyloxazole backbone to engineer donor-acceptor fluorescent pH probes after one- or two-photon absorption. Parent fluorophores, as well as derivatives that can be used to label biomolecules, can be easily obtained in good yields. These molecules exhibit a large one-photon absorption in the near-UV range, and a strong fluorescence emission that covers the whole visible domain. The 5-aryl-2-pyridyloxazole derivatives also possess significant cross sections for two-photon absorption. Upon pyridine protonation, large shifts were observed in the absorption spectra after one- and two-photon excitation, as well as in the emission spectra. This feature was used to measure the pKa of the investigated compounds that range between 2 and 8. In most of the investigated derivatives, the pKa increased upon light excitation and protonation exchanges took place during the lifetime of the excited state, as shown by phase-modulation fluorometry analysis. Several 5-aryl-2-pyridyloxazole derivatives are suggested as efficient probes to reliably measure the pH of aqueous solutions by means of ratiometric methods that are dependent on fluorescence emission.