890136-92-2

Upstream product

• 890136-91-1 2-(2-azidophenyl)-2-(tosylhydrazono)acetic acid 
• 890136-90-0 2-(2-azidophenyl)-2-oxoacetic acid 
• 91-56-5 indole-2,3-dione 

Downstream Products

• 890136-93-3 C₃₃H₃₁N₇O₃S 
• 890137-00-5 3-{2-[[(2-azido-phenyl)-diazo-acetyl]-(1-methyl-1-phenyl-ethyl)-amino]-ethyl}-indole-1-carboxylic acid tert-butyl ester 
• 890136-88-6 2-(2-azido-phenyl)-N-benzyl-2-diazo-N-[2-(1-methyl-1H-indol-3-yl)-ethyl]-acetamide 
• 890136-99-9 C₃₉H₄₁N₇O₅S 

Relevant academic research and scientific papers

Biomimetic approach to perophoramidine and communesin via an intramolecular cyclopropanation reaction

Starting from tryptamine 4 and isatin 5, a biomimetic approach to the pentacyclic substructure 1 of perophoramidine and communesin was developed. The key steps were to create a stable three/six bicyclic system 2 on the 2,3-double bond of an indole derivative 3 by an intramolecular cyclopropanation, followed by ring opening of the resulting cyclopropane ring with the in situ generated amine group of an aniline.