89014-18-6

Usage

Uses

Used in Pharmaceutical Industry:
N-(9 beta-D-2'-deoxyribofuranosylpurin-6-yl)glycinamide is used as a pharmaceutical agent for its potential therapeutic applications due to its unique chemical structure and properties.

Upstream product

• 114988-05-5 3',5'-di-O-acetyl-N⁶-(carbamoylmethyl)-2'-deoxyadenosine 
• 114988-14-6 N⁶-(carbamoylmethyl)-2'-deoxy-3',5'-di-O-isobutyryladenosine 
• 890-38-0 2-deoxyinosine 
• 598-41-4 H-Gly-NH₂ 
• 106568-79-0 9-(3',5'-di-O-acetyl-2'-deoxy-β-D-erythro-pentofuranosyl)-1H-purine-6(9H)-one 
• 114988-03-3 9-(3',5'-di-O-acetyl-2'-deoxy-β-D-erythro-pentofuranosyl)-6-(ethylthio)-9H-purine 
• 114988-11-3 9-(2'-deoxy-3',5'-di-O-isobutyryl-β-D-erythro-pentofuranosyl)-1H-purin-6(9H)-one 
• 114988-12-4 9-(2'-deoxy-3',5'-di-O-isobutyryl-β-D-erythro-pentofuranosyl)-6-O-<(2,4,6-triisopropylphenyl)sulfonyloxy>-9H-purine 
• 958-09-8 2'-deoxy-D-adenosine 

Downstream Products

• 114988-06-6 N⁶-(carbamoylmethyl)-2'-deoxy-5'-O-(4,4'-dimethoxytriphenylmethyl)adenosine 

Relevant academic research and scientific papers

A highly facile and efficient one-step synthesis of N6-adenosine and N6-2′-deoxyadenosine derivatives

(Chemical Equation Presented) A highly facile and efficient one-step synthesis of N6-adenosine and N6-2′-deoxyadenosine derivatives has been developed. Treatment of inosine or 2′-deoxyinosine, without protection of sugar hydroxyl groups, with alkyl or arylamines, in the presence of BOP and DIPEA in DMF, led to the formation of N6- adenosine and N6-2′-deoxyadenosine derivatives in good to excellent yields. Carcinogenic polyaromatic hydrocarbon (PAH) N 6-2′-deoxyadenosine adduct 10 and a rare DNA constituent 11 were thus synthesized directly from 2′-deoxyinosine both in 98% yield.