890171-02-5Relevant academic research and scientific papers
BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
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Page/Page column 25, (2010/11/08)
The invention relates to novel biaromatic compounds that correspond to the general formula (I) and also to the method for preparing them, and to their use in pharmaceutical compositions for use in human or veterinary medicine, especially in dermatology, a
Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease
Webber, Stephen E.,Tikhe, Jayashree,Worland, Stephen T.,Fuhrman, Shella A.,Hendrickson, Thomas F.,Matthews, David A.,Love, Robert A.,Patick, Amy K.,Meador, James W.,Ferre, Rose Ann,Brown, Edward L.,Delisle, Dorothy M.,Ford, Clifford E.,Binford, Susan L.
, p. 5072 - 5082 (2007/10/03)
The design, synthesis, and biological evaluation of reversible, nonpeptidic inhibitors of human rhinovirus (HRV) 3C protease (3CP) are reported. A novel series of 2,3-dioxindoles (isatins) were designed that utilized a combination of protein structure-bas
