890171-55-8Relevant academic research and scientific papers
Chiral Bis(oxazolidine)pyridine-copper-catalyzed enantioselective friedel-crafts alkylation of indoles with nitroalkenes
Sato, Toru,Arai, Takayoshi
supporting information, p. 349 - 354 (2014/03/21)
Catalytic asymmetric Friedel-Crafts reaction of indoles with nitroalkenes was catalyzed by the stereochemically tunable bis(oxazolidine)pyridine (PyBodine)-Cu(OTf)2 complex. Using the PyBodine(Val)-Cu(OTf) 2 catalyst gave the Friedel-Crafts ?adducts with highly enantioselective manner. For the 1,4-bis[(E)-2-nitrovinyl]benzene, the reaction proceeded in a meso-trick manner to give the chiral double Friedel-Crafts adduct with 97% enantiomeric excess. Georg Thieme Verlag Stuttgart New York.
Orthogonal enantioselectivity approaches using homogeneous and heterogeneous catalyst systems: Friedel-crafts alkylation of Indole
Kim, Hun Young,Kim, Sungkyung,Oh, Kyungsoo
supporting information; experimental part, p. 4476 - 4478 (2010/08/20)
(Chemical equation presented) With or without support? The complementary homogeneous and heterogeneous catalyst systems have been developed for the catalytic asymmetric Friedel-Crafts alkylation of indoles with nitroalkenes, in which either of the enantio
Immobilization of diphenylamine-linked bis(oxazoline) ligands and their application in the asymmetric friedel-crafts alkylation of indole derivatives with nitroalkenes
Liu, Han,Du, Da-Ming
supporting information; experimental part, p. 2121 - 2131 (2010/06/15)
A diphenylamine-linked bis(oxazoline) ligand with trans-diphenyl substitution on the oxazoline rings has been immobilized onto one- to three-generation Frechet-type dendrimers and a C3-symmetric core structure. The catalytic activities and enantioselectivities of these new ligands were tested in the asymmetric Friedel-Crafts alkylation reactions of indole derivatives with, nitroalkenes. The two types of immobilized ligands exhibited similar enantioselectivities and substrate compatibilities to the free ligand trans-DPBO we reported previously. No dendrimer effect was observed in the kinetic investigation of the Frechet-type dendrimer-immobilized ligands. The in situ recycling of the catalysts was also tested to illustrate the effect of reducing catalyst loading and the efficiency of our system.
Asymmetric Friedel-Crafts reaction of N-heterocycles and nitroalkenes catalyzed by imidazoline-aminophenol-Cu complex
Yokoyama, Naota,Arai, Takayoshi
supporting information; experimental part, p. 3285 - 3287 (2009/12/01)
Catalytic asymmetric Friedel-Crafts reaction of pyrrole with nitroalkenes was smoothly catalyzed by newly synthesized nitro-substituted imidazoline-aminophenol (1b)-Cu complex to give the adduct with up to 92% ee.
