89020-94-0

Basic information

• Product Name: 2,4-Imidazolidinedione, 5,5-dimethyl-3-[4-[(trifluoromethyl)thio]phenyl]-
• CAS NO: 89020-94-0
• Molecular Formula: C12H11F3N2O2S
• Molecular Weight: 304.293
• Mol File: 89020-94-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4-Imidazolidinedione, 5,5-dimethyl-3-[4-[(trifluoromethyl)thio]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Imidazolidinedione, 5,5-dimethyl-3-[4-[(trifluoromethyl)thio]phenyl]-(89020-94-0)
• EPA Substance Registry System: 2,4-Imidazolidinedione, 5,5-dimethyl-3-[4-[(trifluoromethyl)thio]phenyl]-(89020-94-0)

Safety Data

• Hazardous Substances Data: 89020-94-0(Hazardous Substances Data)

Upstream product

• 15028-41-8 methyl 2-aminoisobutyrate hydrochloride 
• 24032-84-6 4-(Trifluoromethylthio)phenyl isocyanate 
• 13257-67-5 2-amino-2-methylpropionic acid methyl ester 
• 17288-15-2 ethyl 2-aminoisobutyrate hydrochloride 

Downstream Products

• 945257-67-0 1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)thio]phenyl}imidazolidine-2,4-dione 
• 945103-96-8 5,5-dimethyl-3-{3-nitro-4-[(trifluoromethyl)thio]phenyl}imidazolidine-2,4-dione 

Relevant articles and documents

Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors

A new series of IGF-1R inhibitors related to hydantoins were identified from a lead originating from HTS. Their noncompetitive property as well as their slow binding characteristics provided a series of compounds with unique selectivity and excellent cellular activities.

Novel Sulphur-Containing Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors

The disclosure relates to compounds of formula (I): wherein Ra, Rb, R, and n are as defined in the disclosure, to pharmaceutical compositions comprising said compounds, and to processes for making and methods of using the same.