89026-57-3Relevant articles and documents
RuO4-mediated oxidation of secondary amines. Part 1. Are hydroxylamines the main intermediates?
Florea, Cristina A.,Petride, Horia
, p. 475 - 486 (2016/07/20)
The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a and b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a and b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detect
1-Cyanoformamidines. Formation during the RuO4-mediated oxidation of secondary amines
Florea, Cristina,Stavarache, Cristina,Petride, Horia
, p. 319 - 325 (2016/10/11)
When performed in the presence of cyanide and at pH smaller than 5, the RuO4-mediated oxidation of secondary amines Bn-NH-R (1a-b; R=Me, Et) gave mainly 1-cyanoformamidines Bn-NR-C(=NH)-CN (2a-b) and their hydrolysis products Bn-NR-COCN (3a-b), Bn-NR-CN (4a-b), Bn-NR-CONH2 (5a-b). Carboxamides 5a-b can result also directly from 1a-b. (Chemical Equation Presented).