89026-81-3 Usage
Uses
Used in Pharmaceutical Industry:
6-Bromo-2-isopropylaminopyridine is used as a building block for the synthesis of pharmaceuticals due to its ability to react with various nucleophiles. This property allows for the creation of a wide range of drug candidates with potential therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, 6-Bromo-2-isopropylaminopyridine serves as a key intermediate for the synthesis of compounds with pesticidal or herbicidal properties, contributing to the development of effective crop protection agents.
Used in Organic Synthesis:
6-Bromo-2-isopropylaminopyridine is utilized as a versatile intermediate in organic synthesis for the preparation of complex organic molecules. Its reactivity and structural features make it suitable for the construction of diverse chemical entities with potential applications in various fields.
Used in Medicinal Chemistry Research:
6-Bromo-2-isopropylaminopyridine is employed as a research tool in medicinal chemistry, where it aids in the exploration of new chemical space and the discovery of novel bioactive compounds with potential therapeutic benefits.
Used in Drug Discovery:
As an essential component in drug discovery, 6-Bromo-2-isopropylaminopyridine facilitates the identification and optimization of lead compounds, accelerating the process of developing new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 89026-81-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,0,2 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 89026-81:
(7*8)+(6*9)+(5*0)+(4*2)+(3*6)+(2*8)+(1*1)=153
153 % 10 = 3
So 89026-81-3 is a valid CAS Registry Number.
89026-81-3Relevant articles and documents
A practical synthesis of substituted 2,6-diaminopyridines via microwave-assisted copper-catalyzed amination of halopyridines
Mastalir, Matthias,Rosenberg, Egon E.,Kirchner, Karl
, p. 8104 - 8110 (2015/12/30)
A microwave assisted copper-catalyzed amination protocol is reported utilizing a series of 2,6-dihalo- and 2-amino-6-halo pyridine precursors. Using this procedure, selective substitution of one or two halogens by aryl or alkylamines was achieved within 2-6 h with temperatures between 80 and 225 °C affording 2,6-diaminopyridines in good to excellent isolated yields. The reaction allows easy variation between educts and different N-substitutions. The target compounds are valuable precursors for the synthesis of bis-phosphorylated 2,6-diaminopyridines which are used as PNP pincer ligands in transition metal complexes.
BIARYL DERIVATIVES AS GPR120 AGONISTS
-
, (2015/01/16)
The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophages, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steatohepatitis, osteoporosis or inflammation.
