89029-10-7

Basic information

• Product Name: 5,6,7-trimethoxy-2-(7-methoxy-1,3-benzodioxol-5-yl)-4H-chromen-4-one
• CAS NO: 89029-10-7
• Molecular Formula: C₂₀H₁₈O₈
• Molecular Weight: 386.3521
• Mol File: 89029-10-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 576.4°C at 760 mmHg
• Flash Point: 253.7°C
• Density: 1.348g/cm³
• Vapor Pressure: 2.76E-13mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 5,6,7-trimethoxy-2-(7-methoxy-1,3-benzodioxol-5-yl)-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7-trimethoxy-2-(7-methoxy-1,3-benzodioxol-5-yl)-4H-chromen-4-one(89029-10-7)
• EPA Substance Registry System: 5,6,7-trimethoxy-2-(7-methoxy-1,3-benzodioxol-5-yl)-4H-chromen-4-one(89029-10-7)

Safety Data

• Hazardous Substances Data: 89029-10-7(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 22248-14-2 6-hydroxy-2,3,4-trimethoxyacetophenone 
• 5780-07-4 3-methoxy-4,5-methylenedioxybenzaldehyde 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 642-71-7 3,4,5-trimethoxyphenol 

Downstream Products

• 526-34-1 5-methoxy-3,4-methylenedioxybenzoic acid 

Relevant articles and documents

Synthesis and anti-proliferative activities of 5,6,7-trimethoxyflavones and their derivatives

A series of 5,6,7-trimethoxyflavones 1a-1g and their derivatives 2a-2g, 3a-3d, 4 and 5, including the natural products 5,6,7-trimethoxy-4’-hydroxyflavone (1a), 5,6,7,3’,4’ -pentamethoxyflavone (sinensetin, 1 b), 5,6,7-trimethoxy-3’,4’-methyl enedioxy flavone (1c), 5,6,7,3’-tetramethoxy-4,5’-methylenedioxyflavone (1e), 5,6,7, 3’,4’,5’-hextamethoxyflavone (1 g), 5-hydroxy-3,4,2’,3’,4’-pentamethoxy chal-cone (2 b), 5,4’-dihydroxy-6,7-dimethoxy flavone (cirsimaritin, 3a) and 5-hydroxy-6,7,3’, 4’-tetramethoxyflavone (5-demethylsinensetin, 3 b), 3,5,6,7,3’,4’-hexamethoxyflavone (3-methoxysinensetin, 4) and 5’-hydroxy-3,6,7,3’,4’-pentamethoxyflavone (5) were synthesized. Their anti-proliferative activity in?vitro was evaluated against a panel of four human cancer cell lines (Aspc-1, HCT-116, HepG-2 and SUN-5) by the CTG assay. The results showed that most of the synthetic compounds exhibited moderate to high anti-proliferative activities. In particular, compound 3c possess IC50 (5.30 μM) values below 10 μM against Aspc-1 cells and are worthy of further investigation.