89031-97-0Relevant academic research and scientific papers
Catalytic Cleavage of Active Phosphate and Ester Substrates by Iodoso- and Iodoxybenzoates
Moss, Robert A.,Alwis, K. W.,Shin, Jae-Sup
, p. 2651 - 2655 (2007/10/02)
p-Nitrophenyl acetate, p-nitrophenyl hexanoate, and p-nitrophenyl diphenyl phosphate (PNPDPP) were cleaved by o-iodosobenzoate, o-iodoxybenzoate, and 5-(n-octyloxy)-2-iodosobenzoate (3) in aqueous micellar cetyltrimethylammonium chloride solutions at pH 8.The system 3/CTACl was the best catalyst and PNPDPP was the most reactive substrate.In a remarkably rapid hydrolytic reaction at 25 deg C, 1.0*10-5 M PNPDPP was cleaved by 7.14*10-5 M 3 in 2.0*10-4 M CTACl with kφ=1.04 s-1.Experiments in which > demonstrated that the catalyst "turned over"; i.e., degradation of an intermediate phosphate was not rate limiting.
